It's 7:42 PM. A new patient calls your office, and the AI on the line says, "You're all set for Thursday at 10."
The next morning, your front desk opens Dentrix. Thursday at 10 is empty.
The booking went into a separate calendar, or a request queue, or an email. Someone now has to retype it, call the patient to confirm, and hope Thursday at 10 is still open. That's the gap between an AI that integrates with your practice management software and one that actually books in it.
Short answer: we checked 10 AI voice agents' own sites in October 2026. Four say they book, reschedule and cancel in all four systems (Dentrix, Open Dental, Eaglesoft and Denticon) during the call: Callura, Arini, VoxHealth and Dentina. Many others read your schedule, send booking requests for staff to confirm, or rely on a third-party sync. Ask every vendor to book a test appointment on a live demo, then check your PMS.
We've sat through a lot of demos with practice owners, and this is the word that causes the most confusion. When a vendor says it integrates with your PMS, it usually means one of these:
Only the fourth one means your front desk walks in to a schedule that's already right.
| Site says it… | Books into Dentrix | Books into Open Dental | Books into Eaglesoft | Books into Denticon | Books during the call | Reschedules and cancels | Checks insurance eligibility on the call | Signs a BAA | Publishes pricing |
|---|---|---|---|---|---|---|---|---|---|
| Callura | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✗ |
| Arini | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✗ | ✓ | ✗ |
| VoxHealth | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✗ | ✓ | ✗ |
| Viva | ✓ | ✓ | ✓ | ✗ | ✓ | ✗ | ✗ | ✓ | ✓ |
| Dentina | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✗ | ✗ | ✓ |
| Weave | ✓ | ✓ | ✓ | ✗ | ✓ | ✗ | ✗ | ✓ | ✗ |
| Adit | ✗ | ✗ | ✗ | ✗ | ✓ | ✓ | ✗ | ✗ | ✗ |
| Emitrr | ✗ | ✗ | ✗ | ✗ | ✓ | ✗ | ✗ | ✓ | ✗ |
| Smith.ai | ✗ | ✗ | ✗ | ✗ | ✓ | ✗ | ✗ | ✗ | ✓ |
| Mango Voice | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ |
✓ = the vendor's own site or docs say so. ✗ = not stated on the vendor's public site as of October 14, 2026. That doesn't mean the vendor can't do it, so confirm on a demo. Callura's row is ours, and our pricing isn't published yet.
Sources (checked October 14, 2026): arini.ai/blog/ai-phone-agent-for-dental-office; voxhealth.ai/blog/which-practice-systems-the-agent-works-with; voxhealth.ai/security; getviva.ai; dentina.ai; synchronizer.nexhealth.com/case-studies/dentina; getweave.com/ai-receptionist; adit.com/ai-front-desk; emitrr.com/ai-powered-receptionist; emitrr.com/integrations/dentrix; smith.ai/industries/dentists-answering-service; smith.ai/industries/medical-wellness-answering-service; mangovoice.com/support/mango-ai-overview.
Two more names you'll hear. NexHealth isn't an AI voice agent. It's the sync layer several voice agents use to reach your PMS. Retell AI is a platform for building voice agents. It has Dentrix and Open Dental connectors, but you or a partner build the booking yourself.
Callura is an AI virtual assistant for dental practices and med spas, often called an AI receptionist. It books, reschedules and cancels directly in Dentrix, Open Dental, Eaglesoft, Denticon and NexHealth, as well as Zenoti, ModMed, Vagaro and Mindbody for med spas.
Practices are usually live in under a week, with less than two hours of their team's time. Here's what that setup looks like.
For a wider comparison, see our best AI receptionist tools for dental practices, and for nights and weekends, which after-hours answering services book the appointment.
We built Callura because a booking that someone has to retype in the morning isn't really a booking. Slim Dental, the largest dental practice in Manhattan, runs Callura across three locations, and it generates over $1M a year for them. We work with 50+ clinics.
If you're a practice owner who wants every call to end with a real appointment in your real schedule, without changing how your front desk works, you're exactly who we want to work with.
Several AI voice agents say they integrate with Dentrix, but not all of them book the appointment during the call. Callura books, reschedules and cancels directly in Dentrix. See the table above for what other vendors state on their sites.
Yes. Some AI voice agents, including Callura, connect through Open Dental's API, check open slots during the call and write the appointment into the schedule. Others only read the schedule or send booking requests for staff to confirm.
Some do. Callura books, reschedules and cancels in both. Many AI receptionists list Eaglesoft or Denticon as integrations without saying whether they write appointments, so ask for a live test booking.
An integration can mean the AI only reads your schedule or sends requests. Real-time booking means the appointment is written into your PMS while the patient is still on the phone, so nobody has to re-enter it.
No. Callura is built on top of the PMS and workflow you already use. It books into the same schedule your team works from and follows the same rules.
Tell us which PMS you run. We'll show you a booking land in it live.
Callura builds AI virtual assistants for dental practices, med spas and other healthcare practices, trained on each practice's workflows, services and FAQs. They answer calls 24/7, book appointments in your PMS, verify insurance eligibility and send SMS confirmations. Follow Callura on LinkedIn.